• Moobythegoldensock@lemm.ee
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    1 hour ago

    Wong says the team’s new vaccine could also provide protection against coronaviruses that cause influenza and the common cold.

    Ugh science reporting is terrible. “This new tool could stop the cockroaches that cause bedbugs.” See how stupid that sounds?

    Influenza is caused by influenza viruses.

  • DegenerationIP@lemmy.world
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    2 days ago

    They researching for quite a while now. I really hope this will get to the market. Another bonus is, that it theoretically doesn’t need to be rushed.

    But the antivaccines movement will totally Lose it.

  • Disaffected Scorpio@lemmy.world
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    2 days ago

    Hah; I can hear RFK jr already.

    [Gravely voice] “Look if you want to put that unproven poison in your body I would not recommend doing when alternatives exist, like oranges, and Vitamin D, and death.”

  • Harold@feddit.nl
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    2 days ago

    Also, fuck cancer. (Cancer vaccines may be next, the end of the article.)

  • perestroika@lemm.ee
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    Tha’s a new thing for me.

    I wish they had detailed how the removal of glycans is accomplished. Alas, Wikipedia doesn’t even have an article about “glycoengieering”, which would likely be the term for this method.

    Edit: oh, I also mistunderstood. I started thinking that it accomplishes removal of glycans from the invading virus, but instead it’s only removal of glycans from the vaccine, exposing more of the virus, leading to more diverse antibodies. Which is far more doable, and not a big technical novelty. But apparently, quite useful. :)

  • Kazumara@discuss.tchncs.de
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    2 days ago

    Coronaviruses are not the only cause for what is considered the “common cold”. I remember that some Rhinoviruses, Adenoviruses and I think a forth family of viruses also cause symptoms that are counted as a cold. It’s kind of a catch all term.

    • chiliedogg@lemmy.world
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      It includes the latest release, but it’s the same one included on last year’s flu vaccine.

      I think the devs may be quietly winding down support over the next few years.

        • andros_rex@lemmy.world
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          2 days ago

          Abolishes higher education, public libraries, and free time

          Almost like the rise in people identifying as autistic and diagnoses could be connected the fact that we created a non functioning society that only values extraverted people who are willing to lie and hurt others…. That neurodivergence is pathologized primarily because it runs counter to functioning in a capitalist society, and that many autistic people struggling to survive today might thrive and not be seen as even ‘disabled’ in a world where struggling to make eye contact doesn’t get you disqualified in job interviews…

          • eliza_stats@lemmy.world
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            Oh this is a thing I can add to (PhD in Ed here, specialize in ed measurement specifically as it relates to Disabled students across spectrum of disability types). Definitely have ADHD, potentially low support needs AuDHD. Fully adding on to @UnderpantsWeevil@lemmy.world

            This is not exhaustive, it’s not even the most nuanced, it uses a fair amount of terminology from a medical model which isn’t my favorite, but I’m tired and I wrote a lot. This is written from a academic perspective, uses mostly identity-centered terminology, and includes ASD under the Disability umbrella, as that is where it lives from a policy standpoint. For many of us in Education Research, Disability as a term serves as a reminder that the ‘one size fits all’ approach the basics of education policy doesn’t fit particular groups of people in fairly systematic, predictable ways, depending on what their unique needs are.

            -Autism is now understood to be more than just the externalizing behaviors that highlight stereotypes of Autism. While stimming is still a very real indicator, stimming is no longer just hand flapping, head banging, and other large movements- finger/toe tapping, vocal stimms(even quiet ones), fist making, are now broadly acknowledged (among innumerable others), as are internalizing stimms associated with speedy thoughts, maladaptive self-talk, internalized singing, etc. Furthermore, as we now understand just how broad of a spectrum ASD is, we also acknowledge that a huge part of the Autistic population (esp. what are called ‘low support needs’ women, but also broadly across Autistic folx with low support needs/high masking) have primarily internalizing symptomatology both in their stimms, but also their specific interests. Teachers and parents don’t really bat an eye at a young girl who is really into drawing horses, or really loves to write about horses (I swear I’m not picking on horse girls), and loves to read books about horses. Drawing, writing, and reading are acceptable behaviors for girls according to how girls and women are socialized, so it’s largely ignored. Externalizing behaviors and vocal declarations of wants are more encouraged among young boys, until they are deemed problematic for whatever reason.

            -When you remember that all of the ‘gold standard’ ASD screeners were based (almost) entirely on white, male, kiddos, it makes sense that the kiddos whose differences that would be most flagged would be those that align most closely with that demographic. Once upon a time, the ratio of girls to boy with ASD 1:5, it’s now 1:3.8. I anticipate this gap closing further as we understand more and develop better items for screening for internalizing aspects of ASD. Furthermore, different cultural groups have different expectations of behavior (particularly within gendered socialization), and that feeds into differing rates of ASD diagnosis across cultural groups (and the horrifying differences between white and Black kiddos being diagnosed with ASD instead of Conduct Disorder, but that is a much much larger conversation).

            -Starting in the (I want to say late) 90s, Autism screeners became standard practice in early (toddler) pediatric medical appointments. If you (anyone reading) has kiddos, those questions the doctor casually asks you about your child/toddler’s behavior are largely part of different developmental screening batteries. These taper off around 4-5, as typically by that time we have identified a large portion of the higher support needs (level 2 and 3) kiddos. HOWEVER, this is also the time where kiddos are really developing their internal voices, which we’re not really addressing in those caregiver interviews. This means we miss those masking kiddos. As our understanding of ASD expanded into less of a intellectual disability with externalizing behavioral indicators and more into social communication and executive functioning (<- that being a big one) with more internalizing behavior indicators, the number of people diagnosed as Autistic also exploded.

            -Finally, IDEA (now IDEIA) and Rehab Act (Section 504) tied a lot of the funding for supplemental services from the Feds to a diagnosis. The EHA was reauthorized as IDEA in 1990 and that’s when ASD was explicitly added to the list of included Disabilities. 1997 the re-authorization added some supports and need for tracking, and the re-authorization and renaming to IDEIA clarified the importance of IEPs and qualifications for federal funding of services. Funding for services for students qualifying under IDEIA or as English Language Learners are actually the 2 largest (direct student) functions of the trying-to-defunct Dept. of Education. All this to say, in order to receive the appropriate supports for a “fair and appropriate public education” (FAPE, a cornerstone of the Dept. of Ed), diagnosis was rather key. And you see this when you look at the changes in prevalence over time.

            The combination of expansion of the definition of ASD/better understanding the spectrum (ASD becoming more than non-verbal folx with high support needs), coupled with integrated screenings at the doctors office, and then later better identification of internalizing features of ASD (in 2 stages) accounts for a huge proportion of the increases. According to the CDC (these are all for 8 year olds), the incidence was 1:150 in 2000 (for kiddos born in 1992), stayed above 1:100 until 2008 (this is that integrated screenings in peds appointments), and then increased in prevalence again in 2010 (kiddos born in 2002) likely partially attributable to the increase in social communication items on screeners, and then again in more recent years to 1:36 (2020, kiddos born in 2012) (imo ‘omg, girls can be Autistic too’). And all of this is coupled withe some of the legislative changes mentioned earlier.

            And not to ignore the original parent comment: the earliest foundations of formal education systems within the US were definitely to create an ‘appropriately educated’ population during and after the industrial revolution, and that foundation is still very present in formal education. Frankly, ‘back in the day’ those that would be classified as level 2/3 would more often dropped at institutions, generally abandoned, for the state to take custody of, and generally abused and abandoned, there was no real thought to how to integrate them into the industrial revolution at any level. Frankly when the factory education model was developed, Disabled people of any variety were not considered in the slightest.

            PSA: Also note that vaccination counts (as in the number of vaccinations kiddos receive) have stayed fairly stable since like the 1970s. There was a decent jump in 2005, but also some that were dropped off. Not that you could realistically tease out anything close to a causal model looking average vaccinations rates (or counts) with panel data (too many history effects). There are too many other things that support a much more realistic explanation. So with all my heart I remind you all that vaccines don’t cause Autism (I know that was never a question here, but a reminder nonetheless). ETA: Not vaccinating your kiddo because you think vaccines cause Autism implies that you’d rather your child be dead than Autistic, that means you suck.

            Tl;Dr: It’s complicated, race matters, gender spectrum matters, socialization matters, research is slow, follow the money and there is your explanation.

          • UnderpantsWeevil@lemmy.world
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            2 days ago

            the rise in people identifying as autistic and diagnoses could be connected the fact that we created a non functioning society that only values extraverted people who are willing to lie and hurt others

            Or it could be the strict formalization of psychiatric studies, combined with the more broad based diagnosis and categorization of the school aged working class. We’ve invested more labor and professional expertise in analyzing public education and its consequences, so we’re picking up on a wider variety of psychological variants and aptitudes.

            That neurodivergence is pathologized primarily because it runs counter to functioning in a capitalist society

            Capitalists are more than happy to profiteer off of neurodivergence both coming - via commodification of prodigy and other unusual pools of talent - and going - via medical marketing and “normalization” therapies. I wouldn’t say it runs counter to capitalist social agendas, because nothing runs strictly against an agenda that is fixated exclusively on maximizing future profit. We’re continuing to invent exciting new ways to exploit people’s psychological differences, always with an eye towards alienation, segregation, and surplus extraction. Identifying and capturing neurodivegent individuals and squeezing them for their productive value has been a big part of the modern Finance Sector and Silicon Valley projects.

            in a world where struggling to make eye contact doesn’t get you disqualified in job interviews…

            We’re creating a world in which everyone interfaces through computers, where individuals are encouraged to self-segregate and alienate one another, and where information is constantly mediated through attention-grabbing infographic spectacles that reward the users for engagement.

            This is not a system designed to exclude individuals with autism. This is a system designed to feed on them.

            • andros_rex@lemmy.world
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              Or it could be the strict formalization of psychiatric studies, combined with the more broad based diagnosis and categorization of the school aged working class.

              Is autism diagnosis really that formalized?

              I was tutoring psych the other day, and the book the student had still claimed that women were much less likely to be autistic. It’s fascinating how many women don’t get diagnosed well into their thirties. It makes me really wonder what is being used to diagnosis autism, and how much of it might be affected by the tester’s bias and beliefs.

              (Personally, I’ve always wanted to be tested but the 12 month plus waiting list and the $5k not covered by insurance means that I’ll probably continue going through the rest of my life without any form of work accommodation…)

              • eliza_stats@lemmy.world
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                Is autism diagnosis really that formalized?

                Yes, particularly when diagnosed in childhood (especially before middle school). I have a giant ass comment talking about the historical context of changing rates. In theory (like, in this political context who the fuck knows) in order to get formal support as a student or accommodations as an employee, you need a diagnosis. Letters from health providers are part of the process, though some providers are more lax.

                As a hack, @andros_rex@lemmy.world a LOT of the accommodations for ADHD mirror those that are used for those with low support needs and are Autistic, and the comorbidity is really really high (so it might be both). Formal, validated, ADHD screenings can be done online for less than $500 if you have a doctor that will work with you. It might be worthwhile thinking about what kinds of work accommodations you would like, and reviewing ADHD DSM requirements, to see if you might be able to wiggle through that way.

              • UnderpantsWeevil@lemmy.world
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                Is autism diagnosis really that formalized?

                Certainly moreso than a generation ago.

                (Personally, I’ve always wanted to be tested but the 12 month plus waiting list and the $5k not covered by insurance means that I’ll probably continue going through the rest of my life without any form of work accommodation…)

                Not unusual for kids to be picked out in grade school and referred for further diagnosis. But yeah, I can definitely get not wanting to bother going out of pocket on something like that as an adult. Not unless there’s a pressing need.

                • andros_rex@lemmy.world
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                  Not unusual for kids to be picked out in grade school and referred for further diagnosis.

                  Primarily children of one gender presentation, to this day. Which again, makes me very curious as to the validity of the “autism” construct.

  • dryfter@lemm.ee
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    3 days ago

    Meanwhile, in the U.S. I’m sitting here wondering if we’ll even have a flu shot available for next winter, let alone a new vaccine that can protect from Covid and the common cold.

      • FourWaveforms@lemm.ee
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        In the '80s, Reagan thought that AIDS was killing the right people.

        Now it’s the other way around.

        • UnderpantsWeevil@lemmy.world
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          Necessary to protect people with weak immune systems, certainly. But we rarely get better than 60% of the population flu vaxed. It is still vital to deter higher instances of hospitalization and to blunt the rate of spread.

          • AnyOldName3@lemmy.world
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            There are people who have genuine medical reasons to not take vaccines (e.g. an allergy to a common ingredient) or who are so immunocompromised that a vaccine won’t keep them alive, and they rely on other people getting vaccinated to avoid dying. It’s not just antivaxers who antivaxers kill.

            • UnderpantsWeevil@lemmy.world
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              it’s not just antivaxers who antivaxers kill.

              Reminded of the family whose kid died of measles saying “Our other kids survived, so it was fine”.

              That young child wasn’t the one who had been deluded with misinformation.

          • UnderpantsWeevil@lemmy.world
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            Selection bias. All the survivors will say “See! We didn’t need the Fauchi Ouchie!” while all the dead won’t say anything.

            I’ve straight up been at an event where a speaker asked “Raise your hand if you’ve died because you didn’t get vaccinated! Nobody? That’s what I thought.”

            • InverseParallax@lemmy.world
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              2 days ago

              Yes, but we’re slowly evolving away the dumbest and most dangerous of the population.

              In the past we sent them running eagerly into the meat grinder of war.

              Now they’re building up like cord wood, and starting to smolder.

              • UnderpantsWeevil@lemmy.world
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                we’re slowly evolving away the dumbest and most dangerous of the population

                Do you believe that exposure to misinformation is a consequence of genetics? Like, people are just born with an ear uniquely tuned to anti-vax radio, television, and social media?

                Now they’re building up like cord wood, and starting to smolder.

                “RFK Jr is getting his eugenics backwards” is one hell of a take.

                • InverseParallax@lemmy.world
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                  I believe vulnerability to misinformation is an effect of genetics, and this puts pressure on those genes to go extinct as they are not suited for survival.

      • jaschen@lemm.ee
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        They can die from it alone in their house. Stop going to the hospitals and infecting infants and newborns that can’t get it.

    • IphtashuFitz@lemmy.world
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      Latest FDA guidance: Take vitamin A, wash it down with raw milk, and attend virus spreading parties to build natural immunity.

    • partial_accumen@lemmy.world
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      3 days ago

      FDA approval in never.

      I’m not even bothering with FDA recommendations anymore with Kennedy in charge. I’ll be reading the Canada Health and NHS (UK) notices. If it means crossing a national border to get a vaccine, I’m onboard.

      • Ledericas@lemm.ee
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        3 days ago

        there are some international pharm companies that produces vaccines, im sure they wouldnt mind doing it,. glaxo kline smith is one of them, although people have dislike the company for many reasons.

    • Treczoks@lemmy.world
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      Theoretically, this could approved in Europe, which is fine for me. But I doubt the pharmaceutical industry will let a working, permanent immunisation against the common cold happen. That would mean billions and trillions of lost business.

      • Supervisor194@lemmy.world
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        I never understand it when this argument is made. It assumes that there aren’t entities out there making $0 on the common cold that would refuse to take the absolute fucking windfall that would be generated if such an immunization were to be brought to the market.

        Like “oh, you know, we’d like to make this immunization and make billions of dollars ourselves but these OTHER guys are already making billions of dollars and we sure wouldn’t want to step on their toes.”

        • turtle [he/him]@lemm.ee
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          Well, consider all the money that pharmaceutical companies make every year on over the counter medicines for cold symptoms. I’m sure it’s not a perfect example of malfeasance like “hey, we have this perfect cure for the cold in our pockets but we make more profits from our over the counter cold medicines so let’s just bury the cure”, but through a complicated process they often end up at a similar result.

          Recent example: https://www.propublica.org/article/how-big-pharma-company-stalled-tuberculosis-vaccine-to-pursue-bigger-profits

          • HubertManne@piefed.social
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            3 days ago

            I sorta don’t understand this. A TB vaccine has definately been around for awhile and the article does not seem to say what would make this one special. Is it the same vaccine with the thing they says makes vaccines more potent added and they are just not adding it???

            • turtle [he/him]@lemm.ee
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              It sounds like this new vaccine would be 50% effective (including adults?), according to the ProPublica article. The old vaccine, BCG, appears to only be 37% effective on children, not adults (based on a web search - edit: on a second look, different articles are claiming wildly different effectiveness rates for BCG). The disease kills 1.6 million people annually. In other words, it sounds like this new vaccine would save tons of lives compared to the old one.

            • Ledericas@lemm.ee
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              i think only the USa DOESNT routinely vaccinate it against it, because they havnt found much efficacy, TB endemic areas do vaccinate against it, but it has limited efficacy. on the plus side, it is used with cancer therapy as a indirect effect to stimulate the immune system.

        • Treczoks@lemmy.world
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          The point is that some businesses react rather violently on the loss of billions.

      • Ledericas@lemm.ee
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        its pretty hard to vaccinate against the common cold, since coronavirus only represents like 15ish percent, the majority are all rhinoviruses there arnt any vaccines for those because theres too many strains(like 200+) to deal with, and also its so self-limiting its not worht it to produce anyway, in addition to trying to figure out which virus is causing the cold and which strain. also there a bunch of other viruses that causes colds, like entero,adeno, parainfluenza, RSV,etc.

        • Treczoks@lemmy.world
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          I’m well aware of that, but taking only 15% out of a multi-billion-a-year market is still money. And there has been research into dealing with rhinoviruses in general, too, so that would take an even larger chunk.

  • turtle [he/him]@lemm.ee
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    Now consider that Scripps Research, who is developing this, is US-based and receives a lot of federal government funding, and that Trump/Musk/DOGE have been slashing and burning all kinds of federal science staffing and funding. Also consider that their main federal funding comes from HHS, which RFK Jr., notorious vaccine hater, heads.

    Then weep. Progress on this may be stalled for a long time.

      • turtle [he/him]@lemm.ee
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        True, that could also happen, but I wonder how transferable this type of research project is. Does the research lead actually own it and can take it with him or her to a new place, or does Scripps own it? I don’t know the answer.

        • Yeather@lemmy.ca
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          2 days ago

          Flash drive or cloud transfer when you flee the country, the modern replacement for briefcases full of blueprints.

      • Coyote_sly@lemmy.world
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        It’s not an question of if, it’s a when thing at this point. Just like we happily scooped up talent fleeing the Nazis, someone is going to make it easy for highly skilled US citizens to bail. Probably Europe, since they seem to be stepping up to the plate in a lot of ways.