I usually take 20 mg adderall in the morning anytime from 8-9:30 am. The therapeutic effects for the 4 hours that it’s sold as lasting. The problem is that I have difficulty falling asleep 1-2 hours past my bed time.
And I’m going to have to start taking it in the afternoon. I’ve heard eating citrus helps counteract the effects. I’ve tried melatonin, which has helped to a degree
20?? I took 5mg with no ill side-effects.
As someone who’s taken almost every available ADHD medication here’s my 2¢: You might not need 20mg doctors love to over-prescribe that shit. Taking a lower dose (5-10mg) twice a day could be just as effective.
If your mind is racing when you go to bed, the drugs are likely still active. There’s a lot of organizational and motivational methods for getting shit done that will never work for you unmedicated, but could work on lower doses of meds.
Melatonin is a stopgap, you will build a tolerance to it if you try to using it all the time.
Personally I’ve been on atomoxitine (straterra) for the last few months against the behest of my psychiatrist (pill vending machine). It requires more effort and cognizance to still be less effective, but to me it’s worth it to have a “normal” relationship to sleep and food for the first time in almost 20 years.
Ok now for some bad advice: just take niacin to get it out of your system faster. [I have no idea if this works]
Is your aderall XR? Both my kid and I have a combo prescriptions for our ADHD meds. So we take a dose of XR in the morning and an equivalent or lesser dose of immediate release in the afternoon / around lunch. If you’re able to talk to your prescriber about the life schedule change , they may be willing to do this.
Optional side quest: If you are unable to change the prescription, as others have said, you do get used to it with time. It is helpful to be strictly consistent (with ADHD? Ha!) With bedtime and taking supplements to reinforce sleeping at the same time for a while. For me, I take a 10mg XR melatonin most nights, but if I start having a hard time waking up in the morning I swap to 2g Valerian root for a night or two. No idea why this works for me, but I do remember reading at some point that melatonin uses a lot of the same components as dopamine. My personal theory is that eventually I hit a point where because my body barely has to make melatonin with the insane high XR dose, it has more components for dopamine, but eventually this builds up and I become more sensitive to my stimulants and the melatonin, so the Valerian root helps me fall asleep while also forcing my body to make more melatonin.
I’m sure someone who knows more on this topic can provide a better explanation but thats mine.
I find that l-theanine takes the edge off of Ritalin, Adderall. And caffeine. I’ll usually have one around dinner time if want my brain to spin down later in the evening
I’ve found that hydroxyzine can help if you’re feeling too anxious to sleep. Melatonin can help, but usually only when you take it at a consistent time.
Ahhh it’s not over the counter
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For anyone reading, it is the acidity in your stomach from something like orange juice that alters the uptake of amphetamines. Adderall, for example, is a weak base which becomes more ionized in a highly acidic environment and cannot pass through membranes as well.
My question is does Vitamin C only have its effect on the drug during uptake and not after several hours of the drug having passed through your body?
Only during uptake. Once it’s in your bloodstream, the acidity of your stomach and small intestine will no longer play a factor.
I would say uptake happens over 2 hours at most, especially if you’ve just eaten a large meal
No no no and no.
Vitamin C doesn’t do shit.
Citric acid, when in contact with the physical pill, will break it down.
Once there is no more pill, cause its been metabolized, the citric acid in your stomach doesn’t affect it any more.
Once you’ve metabolized it, you’ve metabolized it.
This is only half right, vitamin C does increase the acidity of your stomach. And it is not the physical breakdown of the pill, but how the increased hydrogen ions (H+) bind with the amphetamine molecules and prevent them from crossing your lipophilic GI membranes.

Dope. I’m super not into chemistry, but I saw enough misconception to try and clean up before someone started trying to offset drugs with drugs.
So, lemme poke this a bit…
First, its basically any acid. But stronger means higher impact. Vitamin C is not the important chemical, but it does increase the effect cause its stronger than stomach acid?
Lipophilic… Fat loving… Okay so in the stomach the acid works to neutralize the adderol, but higher acidity means more ionization which makes it harder to absorb through your stomach or intestinal lining?
Are those assumptoons correct?
Still thiygh, once your body has metabolized the adderol into your blood stream, you gotta deal with it being in your blood stream.
Yeah it’s any acid, and I think the acidity actually comes more into play once the drug and the acid enter your small intestine as it’s hard to beat your own stomach acid.
Yeah that second part is right, I don’t really recall the mechanics of it well enough to explain but this gives a pretty good breakdown: https://www.merckmanuals.com/professional/clinical-pharmacology/pharmacokinetics/drug-absorption
If you’re on ADHD meds, then there is a decent chance that you have to stop all cognitive activity by 7pm.
No social media. No work.
Reading a book or going for some exercise is fine.
But if you get your brain running past 7pm, you will have a hard time shutting it back off for sleep.
Also, citrus right before or after brushing your teeth is terrible for them.
You get used to it, it just takes time. You can also ask your prescriber for something to help with sleep. I take trazadone. There’s also nothing stopping you from taking it earlier either, like at 7.
You might try to switch up meds too.
AdderallRitalin felt very “speedy” for me, even the extended release. It releases in 2 waves 4 hours apart.I much prefer concerta which is the same med just with a better release mechanism (steady all day). In my experience ADHD meds are like antidepressants you might have to cycle through a few to find the right fit
Concerta isn’t the same medicine (amphetamine), it’s the other one (methylphenidate). Adderall is actually a non-racemic mixture of amphetamine enantiomers (25% levoamphetamine/75% dexamphetamine), whereas the drug that is the “same” drug is Vyvanse and that’s actually a pure prodrug of dexamphetamine (they call it lisdexamfetamine [with a fucking f!]). Your body turns that into dexamphetamine over time.
My recommendation with Adderall is basically not to get used to taking extended release. The active ingredient is identical between different manufacturers but the time release component can be different. That means that the release profile that you’ve gotten used to over the last six months can dramatically change if you get a different source one month. IR can be a little annoying to remember but I prefer the control it gives you.
If you’re feeling like 20 xr is too much you can switch to 15 xr, but you’re still getting the same delivery profile and also giving up 25% of those sweet sweet drugs. If you get two IR 10s a day, you can take a 10 in the morning and then cut the other in half and titer down your second dose. That way you get the same morning hit as before while reducing the amount you get later in the day. Or you can cut them all in half and do 5/5/5 in closer succession if you feel too amped up off a full 10 in the morning. You also get spare 5mg tablets to stockpile for when there’s a two week delay in getting a refill for no good God damned reason. You can’t do any of that with xr.
Or maybe try a different medication, idk.
Thanks for the correction, I was thinking of Ritalin
Right, Concerta is the slow release form of Ritalin. Some people tolerate that base stimulant better than Adderall for whatever reason. I don’t have any experience with methylphenidate simulants so I can’t speak on them with any authority.
For melatonin make sure you are taking a supplement that only gives you .25-.5mg, more than that can be detrimental. Most supplements do more and there’s some stupid reason why (the correct dose was trademarked or something after an MIT study). Life Science (I think is the brand) makes a vanilla flavored liquid vial, I buy that and do 3-4 drops and the vial last a very long time since the dose is small. I would also consider taking magnesium glycinate at the same time as the melatonin, stuff is very relaxing.
Smoke weed?
I smoke a lot, it doesnt make a dent on the adderall
Damn that fucking blows. It’s the only thing (other than xanax which I refuse to take at any regular interval) that works for me.
And I’m going to have to start taking it in the afternoon.
Are you taking them in the afternoon because that’s when you need the effect, or to try to get sleep? If it’s the latter then that seems counter productive and would probably make it significantly worse. The half life is apparently about 9-10 hours so you want to make sure you’re taking it like 10 hours before you want to fall asleep. Are you on the IR “regular” Adderall or the ER? You might get more bang for your sleepless buck on ER, or just a different drug all together. My friend has better luck on Vyvanse.
I’m ADHD but I’ve never been prescribed meds for it. (although I do drink a lot of caffeine to compensate) The only way for me to get good sleep is to be RIGID with my sleep schedule. I’ll take a melatonin about 1 hour before I want to get in bed. Then I get in bed about 30 minutes to an hour before I want to fall asleep. Staying in bed awake too long can be counter productive. I also need background noise to fall asleep so I’ll play a long video that I don’t really care about/I’ve already seen and isn’t too interesting.
I remember reading the abstract to some studies (which I think I initially saw here) about the effects of Vitamin C on certain ADHD stimulants, in that Vitamin C can reduce the effectiveness of meds and/or counteract compounds in the body. Though I’m not sure exactly which meds are affected and am unsure if it only reduces absorption or actively helps counteract the compounds.
So with that said and taking the above with a grain of salt because i’m a dumbass - maybe some citrus juices or Vitamin C tablets late in the afternoon will assist with winding down?
some more anecdotal statements: I used to struggle with some level of insomnia before i was medicated. I now take 50mg of standard ritalin daily (2 and a half 10mg tabs, twice daily) and I sleep like a rock these days. There are numerous other factors that go into that, but i’ll concur with anyone else who comments that “you eventually get used to it”. I used to lie awake for hours, now I lie down, put on CPAP mask, turn lights off and i swear i drift off within 20 mins
I’d concur—OP might find that the afternoon medication might actually help with settling down and sleeping.
Also if new to the medication, there just might be some acclimation—I had a lot of trouble back in the day when I was starting meds.
Everyone has different reactions/needs from meds, but I’d also recommend looking at extended release versions, I’ve found them a lot less intense and disruptive than when I had regular adderall.











