There is a movie called Good Will Hunting, where the janitor (Matt Daemon) is a math prodigy and befriends a professor therapist (Robin Williams).

This comic is a role reversal of that movie.

Edit: thank you to @mzesumzira@leminal.space for the correction, and the gentle reminder that I need to rewatch this movie. 😁

It’s a reference to the movie Good Will Hunting where Matt Damon is working as a Janitor at a school but solves a teachers “impossible” maths puzzle. The teacher asks who in his class solved it, but nobody stands up (Matt Damon is not in the class)