“This is the first study to show that [the compound] Cu(ATSM) can increase the abundance of P-gp clearance pumps in an Alzheimer’s model, by 24.1 percent, effectively linking the repair of the blood-brain barrier to a reduction in toxic proteins and improved cognitive function,” Dr. Pyun said.

“By improving the pumps, the brain can finally clear out the trapped waste. Over 56 days, the treatment reduced toxic amyloid-beta by 42 percent and improved spatial learning by nearly 44 percent.”

“Cu(ATSM) is a copper compound with anti-inflammatory and neuroprotective properties that has already progressed to clinical testing for conditions like Parkinson’s and ALS,” Professor Nicolazzo said.

    • corsicanguppy@lemmy.ca
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      13 days ago

      10% [success]

      So, the same failure rate as […] many […] vaccines.

      Oh, I’m pretty sure vaccines carry a lot more efficacy than 10%.

      • Logi@lemmy.world
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        13 days ago

        A vaccine’s efficacy is not the same thing as the success rate of a drug going through trials.

    • AA5B@lemmy.world
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      13 days ago

      Even going by the description …… if the problem with Alzheimer’s is the damage is done before you see symptoms, fixing them path to damage can only keep it from getting worse.

      Hopefully we’ll eventually see, but I’m in the camp of the only likely cure being prevention. We already know that some lifestyle changes and vaccinations can lower the risk, even if too many of us can’t fix our habits, and our politico-economy prevents us from doing much about environmental risk factors

      The trick is early testing to find the condition before symptoms, then perhaps a treatment like this article would be useful

      • Rolder@reddthat.com
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        13 days ago

        I wonder what kind of side effects it has. If side effects are minimal or nonexistent, I could see it eventually becoming an OTC thing you just take like a supplement to help reduce your risk in the first place