For me, it would be GLaDOS.
Portal 2 spoiler
She deleted the one remaining human part of herself because it was just too much to deal with. She releases you at the end of Portal 2 as a path of least resistance measure because “killing you is hard.”
What about you, what is your favorite media villain?
I’m going to pick a slightly more obscure one: Kane from Command & Conquer.
Obscure? I think every gamer in my age group (Xennials) knows the leader of NOD.
Kane takes exactly zero shit from anyone
Let’s see Kane deal with Premier Cherdenko.
Bro, Joe Kucan just did not age in that role.
The man really is an alien