That article explicitly says “for PC gaming”. If OP is using this drive for Plex, that’s perfectly supported in the kernel.
Totally agreed this may not be the best distro unless they also have another disk they want to use for gaming, but one benefit is that OP could rebaseline to another Universal Blue OS, or even back to Fedora SilverBlue.

This is not correct.
The Linux kernel has had support for the NTFS file system since 2021. The issues detailed in the article you linked to explicitly refer to issues with Proton and Steam, which require characters that are illegal in the NTFS specification and symbolic links, which the spec does not support.
Sure, you may bump up against these limitations in other apps, but it is a hard crash in Steam and Lutris, which is why the distro has the article.