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2 yr. ago

  • At least in the US, government policy has meant that getting a drug to market is an extremely high bar. This means that funding the wrong drug can waste a billion dollars or more of time, material, trained researchers and lab space, etc.

    Funding drugs by popular attention, private donation, kickstarter, or anything like that is likely to produce a bunch of scams and even more waste.

    Funding drugs by having the government select which ones to study is likely to produce several gigantic financial boondoggles that are dragged on because some Senator wants the jobs wasting the money creates to remain in his state, or something.

    If we want more drugs to come out, the best thing to do would be to reduce the cost of making a drug legal to sell, like by lowering the proof required for efficacy, or by alleviating the doctor shortage by permanently increasing the number of medicare funded residency slots.

  • That's only if it's on a GFI. The resistance to Earth for a typical human is well below the "boy this space heater sure is drawing a lot of power" line that a breaker detects.

  • You can know that it doesn't do something without knowing what it does. For example, there's a light switch in my house in a room with a light. I know that flipping that switch does not turn the light on... But I don't know what it does.

  • In most industries for expensive items, manufacturers devise warranties to run out before the product is broken. Making it longer has a relatively small benefit (consumers might put a little bit more confidence in the longevity of a product with a 25 year warranty than one with a 20 year warranty), and making it too long has a pretty high cost (a bunch of warranty claims).

    Especially if the useful lifetime is not well known, the incentive is for manufacturers to underpromise in their warranties. All of this applied to solar panels sold 25 years ago, and 25 years was long enough to sell people in solar panels and a line of credit as something that would pay for itself. In that context, I think it would be surprising if the panels didn't last far longer than the warranty promised.

  • This could be better than existing pressure balance based mixing systems, assuming it allows you to adjust the hot vs cold pulse width

  • It's the difference between "We must be on God's side" and "God is on our side".

    When the Iraq war kicked off, there was a priest at my parents' church that spoke out against it (as he explained it, "love your enemy" is one of the most challenging things Jesus asked of his followers. It doesn't mean "forgive someone that cuts you off in traffic" it means literally whoever your enemy is, you must love, care for, and protect them, even if it means self sacrifice or dying to do so). Attendance at his sermons dropped by 60 or 70% for years. Eventually I think people started to come around, but he died before there was widespread sentiment against the war. I'm no longer religious, but I miss that priest.

  • Whoever made this picture doesn't know about Fishing Mexico, and I'm disappointed by that.

  • When you account for inflation, oil prices today are in line with oil prices in the early 2000s. The price is too low, and the risk is too high for massive infrastructure spending that would extract more oil from Venezuela to be worth it.

    Possibly, green energy technologies are now on a trajectory to overtake fossil fuels altogether - and they are already a factor in driving the price of fossil fuels (and therefore the profitability of many wells and mines) down substantially. If that happens, the long term value of Venezuela's oil reserves, without suitable infrastructure already built for extraction, could be close to zero.

    In line with small government ideals, the best thing to do is let companies decide whether and how much to invest, but that won't be a headline worth showing off. So Trump is trying to make $100B happen, and believes that that (alone) will restore the Venezuelan economy to the way it was.

  • Easy, when two guys have the same first name, just enjoy them both the same amount. Give good/bad advice to make up the delta.

  • That's 0.000249 - 0.000499 furlongs, but it's probably more helpful to know that it's 0.875-1.75 nails.

  • The language of the post says something that cannot be (meaningfully) derived without a control group of people that didn't experience a counterpoint: "... the situation of being a young woman alone at night in a subway station being enough to generate the sense of fear."

    As I understand it, everyone in the study experienced all of that in combination, so any subset of those things may have been enough to generate a sense of fear: being alone, being at night, being a young woman, or being on a subway station.

    The common objection I see is that everyone feels fear alone on a subway station at night, so the statement is misleading. That matches my personal experience, so I also see that statement as misleading, regardless of any work done by the study.

  • That's a much better question, though! "Here's a stack trace and the source code. Walk me through where to go from here."

    Most places use at least some open source software, so most places can do this, and if you ask your sys admin team nicely, there's probably some stack traces available, hot off the prod.

  • Also, if you put the same wine in different bottles, they pretty reliably prefer (and describe the rich complexities of) the more expensive bottles.

    I knew an audiophile that believed the government had top secret technology for additional audio channels in surround sound setups, like 17.7 or something. I tried very hard to explain how you can buy an off the shelf 128 channel recorder/playback device, and have as many channels as you can feasibly buy and set up, and the reason a lot of media was recorded in 5.1 was because a 5.1 setup was considered at the upper end of what people would be willing to pay for. He moved his target in response, to now the government has top secret 1000 channel audio equipment.

    I don't know what the equivalent of the wine world is, but I hope never to meet it.

  • That's the Medditerain't, right there.

  • I'm sorry for being so much more money for other projects since February.

  • I was raised religious, and fell for the whole "porn makes you unable to form real, properly attached bonds with another human" thing. Then I started reading the scientific background of that stuff, and - while you definitely can damage your ability to form strong relationships with porn (or just about anything else) - that made me far more porn positive.

    Maybe this is just me, but I actually watched/looked at far more porn when I felt deeply ashamed of doing so. Now that I'm OK with it, and it just feels normal, it's comparable to a tool I have access to.

  • We need to ban fully automatic transmissions.

  • rule

    Jump
  • Ugh, not another Truth Social screenshot of Trump.