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1 mo. ago

  • I am always seeking how to provide most societal impact with my work. Writing Wikipedia is cool and useful. But as a one person I can only do so much work and only about topics that I am knowledgeable about. Wikipedia needs much more and better content, and of wider range of topics.

    So I have founded an organization that helps other volunteers to write Wikipedia. The intention is that by doing so, at the end I help Wikipedia grow faster than just by my own writing. Organisation, if done right, has much bigger impact (even per capita) than an individual.

    For similar reason I am thinking about founding a new organization focused on supporting longevity research and public awareness. I mean advanced medical therapies to extent healthy lifespan at least by many decades.

    When thinking about what is going to have biggest impact on human lives in next decades, there are several things. One of them is the option to (if one decide so) live in hight vitality well beyond the age 100. Imagine hitting 80 with health of 40, or hitting 150 with health of 50. Sciencista are already working on that, and current people under 30, maybe even under 40, will quite probably have the option to take such therapies and possibly live a very, very (possibly indefinite, but finite) live. This will change a lot of thing in society as many current social contracts stay on the premise of leaving to pension in 65 and checking out at 85. You may be interested in !longevity@mander.xyz.

  • Well, first of all I see you love your dog and deeply care about 🤗 This is a kind of decision that no one should be forced to face. But nature forces us so...

    When it comes to end of life decision, it is possible to cryopreserve your dog, so in the future, when veterinary medicine advances a lot, they could reanimate your dog and provide many, many more years of healthy life. All the thing about reanimation is still speculative currently (unless your pet is a small worm C. Elegans...). If you are interested, you may search CryoPets and Tomorrow Biostasis. Best luck 🤗

  • In the past I would write Wikipedia or translate libre software. Now I would work on developing Wikimedia and longevity organizations. Especially the engineered longevity have a huge future societal impact.

  • Killing should work for many tissues, especially those whose cells still divide. But for some tissues it is problematic. Killing senescent cell from muscle would make the whole muscle fiber to break. Killing senescent neuron could lead to loose of some cognitive or other function. So part of dealing with senescent cells is to modulate them so they do not vomit senescence associated secretary phenotype (SASP) which is quite annoying to other cells. Ultimately, we could rejuvenate senescent cells so they would work properly, but that seems much harder than other options.

  • That's the intention, but...

  • Yes, the trade is between having color hair or cancer.

  • This is unfortunate. I have read they have some beautiful nature. OK, let's wait but more for that.

  • Playing guitar and singing, recording music, hiking thru forests and camping there, swimming in seas, traveling space.

    And yes, I am actively working to create a world where we do not have much bigger existential risks.

  • I very much agree!

    IMO, as a humankind we need next step in our collective evolution, so we can accept thru as it is and deal constructively with it. Formal school system needs to include education about how to develop emotional inteligencie and recognize manipulation.

  • USA: We will take Danish territory. Denmark: USA is a threat.

    Seems legit.

    It is unfortunate. USA did a lot of great things to humanity. And a lot of shit. I hope that they will succeed to learn from it and restore / create their internal peace (both individual and societal). I really want USA be a friendly ally and a trustworthy partner in making world a better place. And in the meantime let's strengthen Europe, cut many dependencies and rise as the new peaceful and trustworthy global superpower - that's the European destiny 🇪🇺

  • Happens every time. So annoying 😒

  • When old cells are damaged they are at risk of turning into cancer. Many of them rather die (apoptosis) or turn senescent (in that case they can't produce melanin to make color of hair).

  • You get downvoted for clarification of law. Instead of the law itself being downvoted.

  • Then catgirl ears are enough 😉

  • Maybe they should ban using the word "apple" for things made of metal and plastic.

  • Inspiration for many more governments!

    I have already contacted my, Slovakian government. I should ping them again 😅

  • Time for European army. Or at least Army of willing, which can be done without lengthy treaty change process, or dealing on something smaller by all EU members.

  • Or get a catgirl ears. And safer memory.

  • Perverse incentives combined with underskilled management 😐