The UV nail polishes generally have some kind of acrylate. Every time you come into contact with uncured acrylates, there is a chance of developing an allergy to it, which means that the use of medical acrylates becomes much more dangerous if not impossible.
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It's not actually that rare, about 1 in 5 red cats is female. Male turtle shell patterned cars are truely very rare and only occur in chromosomal disorders.