Every single medication has side effects, good and bad. Every medication comes with a product label that goes into the specifics how how the medication works, how it was trialed, how to use it, what to expect, etc. (You can always ask a pharmacist for this if it's not already provided).

The question isn't "do these meds have bad effects", the question is "do the pros of this therapy outweigh the potential side effects?"

NSAIDs like ibuprofen and naproxen are used for pain relief, but they're hard on our bodies and can destroy your liver with chronic use. Yet we can freely buy them as OTC meds.