Arch Linux. First on i3, later on wayland with Sway, where I had lots of flickering, so I’d use XFCE (with x11) specifically for Fusion work (so log out and log in with xfce when i wanted to use fusion). and now Niri, which works well enough for flickering, but has issues with fusion 360’s modal windows not being in the right place, so i use a Labwc window inside Niri and force Fusion to run in that, mostly because i grew tired of switching to xfce. I would recommend xfce if you want less hassle. Haven’t tried with gnome or kde.
Do you remember what issues you had? Whenever i had trouble in the past (e.g. with logging in), i usually found a solution in the github issues (i guess both GH aud codeberg issues now that the project moved)










And you installed all the dependencies listed in the dependencies section and the following section (specifically winetricks and yad)?
Other than that, I never had any trouble installing it.