Total grab bag of random things that immediately come to mind. There’s probably more, but first set that come to mind:

Some apps won’t boot at all (mostly the grocery store apps I was using at time of swap + Costco - though I’ve found the Costco browser experience is actually better than in app).

Some features of apps just don’t load or error out (Thinking insurance and banking apps, especially when trying to sign docs - I expect its them doing a flavor of play store verification that I have blocked at the app level).

I know its possible to set up Android Auto, but I’ve run into some difficulties with it and ultimately determined it wasn’t worth the privacy sacrifices. But the inconvenience of not having Android Auto be plug and play is something a buddy commented on.

There’s not an Assistant search bar in the app tray. This “feature” of stock android is baffling to me. A different buddy commented on it (when I passed them my phone to DJ while I drove) since they usually open the app tray and type the app they want to use (vs finding it in the list).