Probably not a problem for everyone but it was a problem I was running into where my meds weren’t being as effective towards the bottom of the bottle and then would work great after a refill.
My meds are supposed to be stored between 67F and 77F and my apartment has been routinely getting to around 85F for days (and weeks) at a time and by the time I was getting close to the bottom of the bottle it wasn’t really working that well for me.
So I took one of those can fridges and added some temperature control to it to automatically keep it in the temperature range I need and also added a large bag of dessicant in there to keep the humidity low as those little can fridges suck up moisture something fierce.
So basically make sure your meds are stored properly or you’ll probably have some additional issues that you really don’t need.
Fun fact. Lindt doesn’t ship its chocolate during the hot seasons.
Many US food companies won’t ship delicate foods during the hot parts of the year. I have a bunch of my staple groceries shipped to me (go food deserts!) and I can’t get chocolate or other heat sensitive products from them between late May and mid September.
Ritter Sport shipped chocolate with water packs. Probably to keep thr temperature stable.