Bought a new gaming PC with an AMD GPU and went straight for Bazzite almost a year ago. It was pretty damn painless and straightforward. Especially the only thing I use it for are singleplayer or indie multiplayer games. Almost everything worked out if the box.

A lot of sim racing stuff worked surprisingly well.

It was a pain to learn how to install Assetto Corsa with its mods, needs a specific version of proton with specific windows libraries installed, but once I figured that all out it runs great.

It was also a pain when I bought a Chinese handbrake for sim racing, but thanks to the Sim Racing On Linux discord, a member wrote a custom driver for it for me and another member that bought it. Unfortunately, I can't exactly install custom kernel drivers on Bazzite, so I ended up switching to CachyOS and have been enjoying that so far. It was a bit of a pain to switch as it requires more tinkering, but I got to a place where it was running nicely fairly quickly.