I came to say this. And not flippantly. Each one of these takes a dive into the documentation to resolve. Sometimes they are related and you can solve some issues with one change, but each one is a challenge to be solved.
OP, focus on Security first, Errors second, and warnings third. Often the warnings are not a huge deal to having an operational nextcloud, but might impact performance or excessive logging for example.
Many women have their uterus and/or ovaries removed before or during child bearing years due to complications, cancer, etc. So, I'm sure you would change this to say born with to define it. I will say this: not all women are born with this equipment, but are XY on the genotype. I won't even go into the complexities of the genetic side of the house....