Yep, it's a total shitshow with most research and popular science news. More results are coming together about various ND conditions being strictly genetic, yet there's still a ton of people out there talking about what could trigger issues after birth, and cures. You can no more make a zebra into a horse than you can make an ND person into an NT person.
Some of the things people consider issues are unproblematic and natural within ND populations, but NT people rule the world and since they deem it weird, we have to change. I'm at least hopeful that this ND awareness spring we seem to be in, where a lot of adults are becoming aware that they are (and always have been) healthy ND adults, will give rise to some improved acceptance and eventually help shift how we treat ND children to avoid the everyday traumas that I think lead to unhealthy ND adults. I'd be even more optimistic if it weren't for the constant denialism and pushback from everyone, including professionals, and even people gatekeeping in the ND population.
I'm with you, last time an update was this rough for me was like 6+ years ago. That last rough experience had me avoiding major updates until at least 6 months after launch, the only reason I updated was some shitty policy change my corporate IT implemented that wouldn't stop popping up about it.
If you haven't already, force a full rebuild of your spotlight index, https://support.apple.com/en-us/102321 . The only other advice aside from rollback or reinstall is to create a new user profile.