Pretty sure he's only in a defensive posture because the plate was just plopped right in front of him. Crayfish are cannibalistic scavengers so this would actually be a welcome sight.
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In cases of cellular stress p53 is activated via phosphorylation. It will then direct the cell to pause its division and to either undergo DNA repair or kill itself. p53 is one of the body's most important defences against cancer. Mutations causing p53 dysfunction are found in more than half of cancer cases.