I don't get too emotional at games, but I do at music.... and even though I was laughing my ass off with joy at Metal Gear Solid 2, I cried at the ending because I just enjoyed it so much and the music hit me in the feels.
Other than that... not really. I had the most emotional investment in a game with the Mass Effect series, but by the end of 3, I was kinda checked-out when everyone was getting offed. I was already over it.

What's the long-game, man?
Like, he dies and we just mop up Trump's bullshit with the new guy's bullshit?
Wait, that's literally how history works.