I'm testing it right now and it seems to work: I randomly clicked on a game cover that looked ai generated and had the pop-up message: https://zealxy.itch.io/till-checkout-do-us-part
Then i went to my own ttrpg page (i know it has no AI in it, and i know I didn't check the AI box) and it didn't trigger the pop-up: https://rhaxapopouetl.itch.io/vain-pirates-of-the-seven-seas
I tried a few other itch.io pages and it seems to work well.
I love this man. His video are always a treat.