I mean, Australia is one of the best places in the world to send nuclear waste. Seismically inert, sparsely populated in remote areas, strong regulatory competency to ensure a compliant industry. With it buried deep underground, life on the surface won’t be affected nor will the hydrology.
I first try to think of the broad headings. If I can’t do that yet, I write out dot points of my ideas and see if I can group them.
Next, I start expanding the headings out with as many dot points as I need.
When I want to add more detail to a dot point, I indent that further, or write a sentence/sentences under it.
When I’ve got sentences for everything, I start to remove the scaffolding and group into paragraphs.
Example
Say I want to write a how-to guide to change a car tyre. I initially think of two main things:
Tools required
Procedure
Now, let’s add some dot points
Tools required
Jack
What is it?
Where to find it?
Tyre wrench
What is it?
Spare tyre
Does your car have one?
Differences between spare tyres and normal tyres
Procedure
Prepare the car
Prepare the jack
Jack up the car
Remove the tyre nuts
Remove old tyre
Place new tyre
Tighten nuts
Check tightness
Lower the car
Test new tyre
Notes
Plan to replace spare tyre if used
What if you have no spare tyre?
Notice how I added a new heading when a thought came to mind?
Now I’ll keep adding detail until I’ve got paragraphs.
Tools required
Jack
What is it?
A jack is a device you use to raise the car wheel up above the ground so you can change the tyre.
Where to find it?
You can usually find the car jack in the boot of your car, but check with your vehicle owners manual for specific locations. Your car might not have a jack, in which case you will need to source one from elsewhere.
Safety
Jacks carry significant weight, so can be unsafe if damaged or not set up properly. Check that your jack isn’t damaged before using it. Moreover, you will need to ensure your jack isn’t on a slippery surface or a surface that could be damaged by it. In that case, you can place a plank of wood under the jack.
Tyre wrench
What is it?
Spare tyre
Does your car have one?
Differences between spare tyres and normal tyres
Procedure
Prepare the car
Prepare the jack
Jack up the car
Remove the tyre nuts
Remove old tyre
Place new tyre
Tighten nuts
Check tightness
Lower the car
Test new tyre
Notes
Plan to replace spare tyre if used
What if you have no spare tyre?
Then keep doing this until you’ve finished it! Remember it’s normal to rearrange things as you go.
Oh we already know this. There are parts of the genome that, if even slightly changed, cause terrible, terrible things.
Mutations can happen anywhere, but serious mutations (that may affect the basic things a cell needs to do in order to exist) result in cell death and therefore don’t manifest in the population — the population continues on as though the mutation had never existed.
In this way, natural selection conserves some parts of the genome while less essential parts can vary more freely without being deleterious to the organism.
For example, most non-bacteria (including all plants, animals, fungi, protists) have special proteins called histones. Histones are used to package the DNA together and wrap it all up. Cells can’t function at all without a these proteins, and the most important histone proteins evolve so slowly that they’re almost identical between a human and a pea. (Humans and peas shared a common ancestor over half a billion years ago.)
ETA: My molecular biology knowledge is rusty, but IIRC the way DNA is packaged and unpackaged can also reduce or increase the risk of DNA being exposed to potential mutagens. So if it’s wrapped up, it’s harder to access and tamper with
Me: how many applications have you got installed? SimplyMepis: Yes.