Seems like Cafestol (the oil in unfiltered & french press coffee) rises cholesterol level. On the other hand, coffeine might trigger the mTOR mechanism in cells (starving does that usually), leading to cells cleaning better up, lowering oxidans levels, potentially raising life expectancy. Other studies say, coffeine induces apoptosis (programmed cell death) with the same mechanism. Apparently a mixed bag.
But wasn't there a study lastly, that the stimulating effect only works if you don't drink coffee regularly, while if you do and don't drink coffe, you get withdrawal symptoms, like having no energy, needing a coffee.
Did i miss anything?
For me, that (and reading about the ecological footprint of drinking coffee) lead to drinking barley coffee/tea regularly. And a coffee if i really need one.
Only thing i saw here are general answers. /run/user/1000 resp. $XDG_RUNTIME_DIR is a tmpfs (somt. like a ramdisk) created by PAM (pluggable authentication module) on login, 1000 being your user id. It is more restricted in security and size than cache and should be used for small files where quick access or security matters. A common example are sockets.
You can delete it, it will just be regenerated next log in, but your very session will run into trouble, you should log out after (if you don't just get booted out, that is).
And yeah, like others said; this is not Windows, you don't have to, and shouldn't, clean up anything outside your home dir.
You can be sure that everyone possessing more than a 100 million has a skeleton in the cupboard.