I’ll always remember chatting with a guy at the airport who asked what I was in grad school for. Unexpectedly, he was thrilled to talk about neuroscience, and asked what I thought of a recent study. Some researchers had put dogs in fMRI to “prove” that dogs can feel love.

Szechuan peppercorns. They do not contain capsaicin, but produce a vanilloid drug that opens potassium leak channels in your mouth, preferentially in the fine touch afferents. When you eat szechuan spice these neurons misfire and tell your brain that you are sensing a rapid, fluttery (50Hz) vibration.

Also called Chinese prickly ash, these trees are not related to chili peppers or black pepper, but are instead very small citrus fruit. Fears over them introducing citrus blight led to a ban on imports to the US that was only overturned in 2005. Since then, people like me have been discovering how good they are in pasta sauce.

There is good reason to limit off-target drug delivery, to minimize side effects in tissues that don’t need exposure to the drug.

• Is the oral route more effective than topical?
• What are the systemic effects of the oral med?
• Was the study quoted in the article in any way funded by a pharmaceutical company that would be granted an exclusive license for a “new formulation,” or is it trustworthy?

The art also serves to promote her onlyfans. Do you think her lighter brunette friend is on there too?

non-paywalled link

tl;dr Pottery kiln is 100y older, reshapes understanding of Bedfordshire’s historic pottery industry

RFK Jr would like to remove scientific scrutiny from the drug approval process, which is the agenda of pharma companies. He’s already been successful with this in the med device space using the same argument.

On a plane, the head mount goes backwards on the head of the passenger seated in front of you. Great for relieving wrist strain

Australian psychedelic bands are awesome. See also: ORB, Beans, Pyschedelic Porn Crumpets, Jagwar Ma

Brain-imaging evidence showed that the subjects’ parietal lobes, involved in spatial reasoning, were more active during approximation problems; while the left inferior frontal lobes, involved in verbal reasoning, were more active during exact calculation problems. Studies of patients with brain lesions paint the same picture: those with parietal lesions sometimes can’t decide whether 9 is closer to 10 or to 5, but remember the multiplication table; whereas those with left-hemispheric lesions sometimes can’t decide whether 2+2 is 3 or 4, but know that the answer is closer to 3 than to 9.

I wonder if, in the face of very large numbers, both these systems fail and we default to a social/emotional impression of “powerful/scary.”

Looks great, but tangled. Where do you go from here? Will they not choke each other out?

Software engineering back then sounds like academia

“Set” (v. intransitive) literally always refers to orbital bodies becoming occluded by a horizon. She knew this

My new favorite 405 image