Do you have adaptive sync on? If you do try turning it off for both monitors. That worked for me but your milage may vary.
I second Mapocolops, all of his souls lets plays are great. He's one of the few lets players that actually reads item descriptions and tries to understand the story and lore.
𝓸𝓱, sᴉɥʇ ᶦˢ ʳᵉᵃˡˡʸ ç̷̖͉̣̮̰̳̞̙̻̖̳̺̊̆̒̀͊̇͑̅͂͒̓͟͠o̷̧͇̟̝̲̦̯̜͕̹͒̅̏̾̓̓̂̌̍̕͜ȏ̴̡̗̬̺̱̘͎̹͉̥̿̀̔̌̎̑̅̒̉̂̕͜͝͡l̸̥̞̿̊̽̾̓̉̍̒͋.̼
Do you have adaptive sync on? If you do try turning it off for both monitors. That worked for me but your milage may vary.