So it turns out that phenylephrine spray (i.e. topically applied) is actually super effective. It only lasts for a couple hours, although it's insanely fast to start working.
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There's been some effort in relation to defending against another Schedule F.
https://www.govexec.com/workforce/2024/10/opm-issues-guidance-agencies-implement-anti-schedule-f-regulations/400618/